These are the keyboard shortcuts I use to make ArcMap a little more illustrator-like. I think learning keyboard shortcuts is crucial to becoming more efficient and once you get in the habit and practice/force yourself to use them, it will pay dividends in productivity.
To set them up, in ArcMap, go to Customize>Customize Mode and in the Customize window, hit the Keyboard… button. Type in the first line from each group below, choose the right category, click on the command, perform the keystroke, then hit assign.
My shortcuts are presented in three lines each with the following format:
zoom whole page
save a copy
bring to front
send to back